A glucuronide metabolite of tigecycline, and its corresponding epimer, have been identified in humans treated with tigecycline. Mass spectral data have been used to identify these structures.

A method for preparing n-acetylglucosamine starting from glucosamine base having a purity level of at least about 99 wt. % and a maximum halide content of about 0.01 wt %. The glucosamine base is slurried in a diluent comprising a C.sub.1-C.sub.4 straight or branched-chain alcohol, e.g., isopropyl alcohol, sec. butyl alcohol, tert. butyl alcohol, etc. Thereafter, an acylating agent, e.g., acetic anhydride, present in at least a stoichiometric amount, is slowly added to the slurry while maintaini...

A spherical cellulose material wherein the cellulose material is a water-insoluble polysaccharide formed by .beta.-1,4-type sugar chain linkages, the degree of crystallinity is 70% or greater, and macrofibrils are formed radially from the center to the periphery.

Triple derivatives of polygalactomannan i.e., dialkylaminoalkyl ether-hydroxyalkyl ether - long aliphatic chain ether of polygalactomannan, are useful as thickening agents for aqueous fluids.

4,6-O-hydroxyphosphoryl-glucosamine derivatives as shown in the following formula [I] and their pharmaceutically-acceptable salts: ##STR1## wherein R.sub.1 and R.sub.2 represent a hydrogen atom or a hydroxy group; one of R.sub.3 and R.sub.4 represents --OCO(CH.sub.2).sub.n CH.sub.3, --CH.sub.2 (CH.sub.2).sub.n CH.sub.3, or --O--CH.sub.2 (CH.sub.2).sub.n CH.sub.3, and the other represents a hydrogen atom; l is an integer of 4-16; m is an integer of 4-16; and n is an integer of 6-18.

A crosslinked product of a primary amino group-containing compound such as proteins, chitosan or a mixture thereof is disclosed. The product has a crosslinked structure formed by crosslinking with an iridoid compound, and the blue color developed by the crosslinking is decolorized. Also, a method for decolorization of the above crosslinked product is disclosed. The method comprises reacting a crosslinked product obtained by crosslinking a primary amino group-containing compound with an iridoid c...

The present invention relates to an efficient new route for the preparation of (+)-nojirimycin and (+)-1-deoxynojirimycin which involves the stereoselective reductive amination of 1,2-O-isopropylidene-5-oxo-.alpha.-D-glucuronolactone. The reductive amination uses particular oximes of the 5-oxo compound.

Octyl ethers and octadienyl ethers of glucose, sucrose, are disclosed. Compositions comprised of a mixture of octyl ethers of glucose and sucrose and those containing octadienyl ethers of sugar acids are also disclosed.

Alkyl glycosides and alkyl oligoglycosides of low iodine color number can be prepared by acid-catalyzed condensation of saccharides in an aqueous solution with short-chain alcohols at elevated temperature in a counter-current reaction column.

The present invention relates to compounds of the formula I wherein if m stands for 1, then R represents a group derived from a mono- or di- or oligosaccharide by removing the hydrogen atom from the hydroxyl group being in the 1(alpha) or 1(beta) position, or the O-protected, preferably acetylated derivative thereof, if m stands for 2, then R represents a group derived by removing a hydrogen atom attached to the carbon atom being in position 1 of the reaction product of glucose and mono-, di- or...