A proteinaceous cardioactive factor that exhibits positive inotropic activity and positive chronotropic activity has been partially extracted from mammalian plasma by precipitation with polyethylene glycol followed by cation exchange chromatography. The factor may be fractionated into two active fractions, one having an apparent molecular weight of about 130,000 daltons and the other having an apparent molecular weight of about 30,000 daltons, by gel filtration chromatography.

A method for treating anemia comprises administering an atrial natriuretic factor (ANF) alone or in combination with erythropoietin (Epo). The ANF potentiates the activity of Epo and causes production of erythroid progenitors, BFU-E and CFU-E, and as a consequence red blood cell production at greater levels than if Epo alone is present in the blood stream.

A peptide analogue of mammalian insulin-like growth factor-1 wherein from 1 to 5 amino acid residues are absent from the N-terminal.

A new immunosuppressive factor derived from human T cell leukemia cells characterized by the following properties: (1) molecular weight: 45,000 to 65,000 daltons and 150,000 to 200,000 daltons by gel filtration, and approximately 31,000 daltons by SDS-polyacrylamide gel electrophoresis; (2) isoelectric point: 4.6 to 4.8; (3) being elutable at a concentration of 0.31 to 0.32 M sodium chloride by FPLC-Mono Q anion exchange chromatography; (4) not adsorbable to immobilized concanavalin A Sepharose ...

Method of and apparatus for measuring thermal radiation geometric configuration factors -- any such factor being that fraction of the total radiant energy emitted from an energy-radiating surface which is incident on an energy-receiving surface. The method includes the steps of forming an image of the projected area of an energy-radiating surface at a selected location along an energy-receiving surface, making a photographic reproduction of such image, repeating the image-forming and image-repro...

A limiter circuit receives a distorted or unsymmetrical input signal, and in response thereto produces a rectangular current waveform. The rectangular current waveform is applied to an integrating means for generating a triangular waveform, the average value of which divides such triangular waveform into equal time intervals. This triangular waveform is a.c. coupled to a second limiter circuit which provides an output waveform characterized by a fifty percent duty factor.

A switch apparatus is described including a rotary switch operated by a knob having a movable dial flange with display characters thereon at switch positions corresponding to different multiplying factors provided for the output signal of an electrical circuit controlled by such switch. A pair of fixed light sources mounted at two different readout positions beneath the flange are selectively energized by an external multiplier switch to illuminate only one of the factors at such readout positio...

Power factor measuring apparatus receives voltage and current input signals representative of the voltage on and the current in a power line and derives rectangular voltage and current pulses from half cycles of one polarity of the input signals. The timing cycle of an adjustable timer is initiated by the crossing of the zero axis by one of the input signals, and a clocked flip-flop receiving the timer output on its clock input and the rectangular pulse derived from the other input signal on a s...

A method of treating human patients suffering from immune deficiency diseases by extracting a "transfer factor" from leucocytes obtained from healthy donors who exhibit immune response to said diseases and injecting said "transfer factor" into said diseased patients to thereby suppress disease symptoms.

A quick-dissolving antihemophilic factor preparation is obtained by adjusting the pH of buffer-extracted plasma cryoprecipitate to from about pH 6 to about pH 7.0 and cooling to a temperature of from about 2.degree.C to about 20.degree.C for from about 15 minutes to about 1 hour, in order to precipitate certain protein impurities, primarily fibrinogen.