The present invention relates to pharmaceutical compositions comprising a positive modulator of a nicotinic receptor agonist, said positive modulator having the capability to increase the efficacy of the said nicotinic receptor agonist.
The invention provides a method of treatment or prophylaxis of obesity, comprising administering to a patient in need of such treatment a therapeutically effective amount of an aryl sulfonamide compound of formula (I) or formula (II) ##STR1## wherein the substituents are as described in the specification.
Novel diketones of the structure ##SPC1## Or a tautomeric form thereof in which R.sup.1 and R.sup.2 represent hydrogen or lower hydrocarbyl groups with the proviso that the number of carbon atoms of R.sup.1 and R.sup.2 taken together is from 1-4 R.sup.3 represents a hydrogen, acyl or alkyl group containing 1-24 carbon atoms R.sup.4 represents an alcohol protecting group resistant to alkali but removable under acid reaction conditions Z represents an oxygen or sulphur atom are claimed and a proce...
Disclosed is a process of improving the adhesion of polyester material to various other materials using the azidoformates of omega-hydroxyalkyl phthalates, their related low molecular weight condensation polymers and their mixtures represented by the general formula ##SPC1## Where R is an alkylene radical containing 2 to 10 carbon atoms and x is an integer of from about 1 to about 10. In particular, there is disclosed a process of improving the adhesion of polyester tire cord to rubberr tire sto...
The adhesive properties of compositions which contain an organic isocyanate, with or without a film-former, are improved by the inclusion of (a) an aliphatic hydrocarbyl nitrite or (b) a nitrite ester of a carbamic acid which acts as an adhesive promoter. The compositions are useful for adhering natural and synthetic polymeric elastomers, and are particularly useful in the production of laminations formed from polyurethane polymers and other substrates including metals, etc. and especially the f...
Disclosed is a process of improving the adhesion of polyester material to various other materials using the azidoformates of omega-hydroxyalkyl phthalates, their related low molecular weight condensation polymers and their mixtures represented by the general formula ##SPC1## Where R is an alkylene radical containing 2 to 10 carbon atoms and x is an integer of from about 1 to about 10. In particular, there is disclosed a process of improving the adhesion of polyester tire cord to rubber tire stoc...
There are disclosed novel 3-amino(and substituted amino)-hydroxy (and dihydroxy)-1,2,3,4-tetrahydrocarbazoles having positive inotropic activity and methods and compositions for the use thereof in treating the failing heart in mammals afflicted with congestive heart failure.
Sterol glycosides and esters thereof with monocarboxylic acids of natural or synthetic origin are used to combat human and animal illness in dosages of not over 10 mg per day.
New penicillins of the formula ##STR1## in which ##STR2## E is oxygen or sulphur, and R.sub.1 and R.sub.2 are hydrogen or various organic radicals with certain provisos, or salts thereof, are antibacterially ative and useful as antibiotics in pharmacy, as animal feed supplements for promoting growth, and as preservatives.
