The heart catheter has at least one electrode pole, which is arranged on a spreadable device at the distal end of a catheter shaft. The device comprises at least two struts manufactured from an elastic material, which can be spread out following the contours of a cavity of the heart, in particular of a vestibule. Means are provided with which the electrode pole is displaceable along a strut.

The invention provides for an input/output circuit in a CMOS integrated circuit which can withstand pad voltages which are higher than the supply voltages for the integrated circuit. The input/output circuit has a pair of first polarity-type transistors which is connected in series between a first supply voltage terminal and the input/output pad, and a pair of second polarity-type transistors which is connected in series between a second supply voltage terminal and the pad. Responsive to a disab…

This invention provides for recombinant single chain antibodies capable of specifically binding to a Lewis.sup.Y -related carbohydrate antigen and fusion proteins comprising these antibodies. More particularly, the invention provides for single chain Fv regions of the monoclonal antibody B3. The invention also provides for a method of improving the binding affinity of antibodies lacking a serine at position 95 of the V.sub.H region that involves mutating position 95 to a serine.

An access catheter for percutaneously connecting to a subcutaneously implanted port comprises a catheter body having a distal end and a proximal end. A needle or other access tube is connected to the distal end of the catheter body through a fitting, optionally at a right angle relative to the catheter body. A compressible element impregnated with an antiseptic, antibiotic, anesthetic, or other active agent, is provided adjacent the distal end of the catheter body and surrounding the needle. Whe…

Systemic delivery of insulin to a mammalian host is accomplished by inhalation of a dry powder of insulin. It has been found that dry insulin powders are rapidly absorbed through the alveolar regions of the lungs.

A high-performance flip-flop circuit implementation. The flip-flop circuit comprises an “implicit” one-shot to generate a delayed clock output (407). The flip-flop comprises a delay block (405) coupled to a clock input (210). The flip-flop may be a D-type flip-flop. In a positive-edge-triggered embodiment of the flip-flop, a falling edge (540) of the delayed clock output (407) follows a rising edge (544) of a clock signal after a delay period (548). The flip-flop clocks in new data at a data inp…

The present invention provides a process for preparing compounds of Formula I: ##STR1## wherein R.sub.1 is methyl by reduction of a camphene intermediate with a reducing agent.

A method of manufacturing quantum structures, in particular quantum dots and tunnel barriers and also a component with such quantum structures wherein in that a substrate is structured by the intentional formation of trenches so that material remains between oppositely disposed trench sections, with a transition from a broader region to a narrower region; wherein further material is deposited onto the substrate so that differential growth sets in on the remaining regions of the substrate and an …

Dry powders of .alpha.1-antitrypsin are administered pulmonarily to patients to treat, for example, certain types of emphysema. The dry powder compositions may comprise aggregates of fine particles, which aggregates are friable and break-up upon dispersion in a flowing gas stream. Typically, the dispersed powders are captured in a chamber and subsequently inhaled by a patient for pulmonary treatment of emphysema and other conditions.

A portable, multi-purpose exercise system that includes dumbbell bars configured for interconnection to form a barbell and a plurality of hollow, rigid discs configured for attachment to the dumbbell bars. The discs are fillable with water to provide a consistent and accurate amount of weight. The discs and dumbbell bars are stored within a portable transport and storage case that may be used as a bench for weightlifting exercises and a bench step for aerobic exercise. A headrest is included tha…